Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

Genome sequencing has revealed a large number of shared and personal somatic mutations across human cancers. In principle, any genetic alteration affecting a protein-coding region has the potential to generate mutated peptides that are presented by surface HLA class I proteins that might be recogniz...

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Detalhes bibliográficos
Main Authors: Rajasagi, Mohini, Shukla, Sachet A., Fritsch, Edward F., Keskin, Derin B., DeLuca, David, Carmona, Ellese, Zhang, Wandi, Sougnez, Carrie, Cibulskis, Kristian, Sidney, John, Stevenson, Kristen, Ritz, Jerome, Neuberg, Donna, Brusic, Vladimir, Gabriel, Stacey, Lander, Eric S., Getz, Gad, Hacohen, Nir, Wu, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102716/
https://ncbi.nlm.nih.gov/pubmed/24891321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567933
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