Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

Genome sequencing has revealed a large number of shared and personal somatic mutations across human cancers. In principle, any genetic alteration affecting a protein-coding region has the potential to generate mutated peptides that are presented by surface HLA class I proteins that might be recogniz...

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Détails bibliographiques
Auteurs principaux: Rajasagi, Mohini, Shukla, Sachet A., Fritsch, Edward F., Keskin, Derin B., DeLuca, David, Carmona, Ellese, Zhang, Wandi, Sougnez, Carrie, Cibulskis, Kristian, Sidney, John, Stevenson, Kristen, Ritz, Jerome, Neuberg, Donna, Brusic, Vladimir, Gabriel, Stacey, Lander, Eric S., Getz, Gad, Hacohen, Nir, Wu, Catherine J.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2014
Sujets:
Transplantation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102716/
https://ncbi.nlm.nih.gov/pubmed/24891321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567933
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