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Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis
Cell cycle inhibition has yet to offer a generally effective approach to cancer treatment, but a full evaluation of different combinations of cell cycle inhibitors has yet to be evaluated. Cyclin A2, a core component of the cell cycle, is often aberrantly expressed in cancer where it may impact cell...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102624/ https://ncbi.nlm.nih.gov/pubmed/24802190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3440 |
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