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Cdk2 and Cdk4 Activities Are Dispensable for Tumorigenesis Caused by the Loss of p53
The loss of p53 induces spontaneous tumors in mice, and p53 mutations are found in approximately 50% of human tumors. These tumors are generally caused by a number of events, including genomic instability, checkpoint defects, mitotic defects, deregulation of transcriptional targets, impaired apoptos...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682046/ https://ncbi.nlm.nih.gov/pubmed/19307310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00952-08 |
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