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The Stretching Frequencies of Bound Alkyl Isocyanides Indicate Two Distinct Ligand Orientations within the Distal Pocket of Myoglobin()

The FTIR spectra for alkyl isocyanides (CNRs) change from a single ν(CN) band centered at ~2175 cm(−1) to two peaks at ~2075 and ~2125 cm(−1) upon binding to sperm whale myoglobin (Mb). The low and high frequency peaks have been assigned to in and out conformations, respectively. In the in conformat...

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Detalhes bibliográficos
Main Authors: Blouin, George C., Olson, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102131/
https://ncbi.nlm.nih.gov/pubmed/20476740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100172c
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