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Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time
Non-homologous end joining (NHEJ) is the major pathway for repair of DNA double-strand breaks (DSBs) in human cells. NHEJ is also needed for V(D)J recombination and the development of T and B cells in vertebrate immune systems, and acts in both the generation and prevention of non-homologous chromos...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102006/ https://ncbi.nlm.nih.gov/pubmed/24656613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.02.009 |
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