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A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and Ku heterodimer together form the biologically critical DNA-PK complex that plays key roles in the repair of ionizing radiation-induced DNA double-strand breaks through the non-homologous end-joining (NHEJ) pathway. Despite elegant and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045832/ https://ncbi.nlm.nih.gov/pubmed/21030321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.09.019 |
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