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A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and Ku heterodimer together form the biologically critical DNA-PK complex that plays key roles in the repair of ionizing radiation-induced DNA double-strand breaks through the non-homologous end-joining (NHEJ) pathway. Despite elegant and...

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Hlavní autoři: Dobbs, Tracey A., Tainer, John A., Lees-Miller, Susan P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045832/
https://ncbi.nlm.nih.gov/pubmed/21030321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.09.019
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