COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients

BACKGROUND: The majority of Osteogenesis Imperfecta (OI) cases are caused by mutations in one of the two genes, COL1A1 and COL1A2 encoding for the two chains that trimerize to form the procollagen 1 molecule. However, alterations in gene expression and microRNAs (miRNAs) are responsible for the regu...

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Hauptverfasser: Kaneto, Carla M, Lima, Patrícia SP, Zanette, Dalila L, Prata, Karen L, Pina Neto, João M, de Paula, Francisco JA, Silva, Wilson A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101867/
https://ncbi.nlm.nih.gov/pubmed/24767406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-15-45
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