COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients

BACKGROUND: The majority of Osteogenesis Imperfecta (OI) cases are caused by mutations in one of the two genes, COL1A1 and COL1A2 encoding for the two chains that trimerize to form the procollagen 1 molecule. However, alterations in gene expression and microRNAs (miRNAs) are responsible for the regu...

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Bibliografiske detaljer
Main Authors: Kaneto, Carla M, Lima, Patrícia SP, Zanette, Dalila L, Prata, Karen L, Pina Neto, João M, de Paula, Francisco JA, Silva, Wilson A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101867/
https://ncbi.nlm.nih.gov/pubmed/24767406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-15-45
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