Intrauterine Bone Marrow Transplantation in Osteogenesis Imperfecta Mice Yields Donor Osteoclasts and Osteomacs but Not Osteoblasts

• The goal of osteogenesis imperfecta (OI) cell therapy is osteoblast replacement; • In utero transplantation (IUT) of bone marrow was conducted in OI mice; • Donor-derived osteoblasts were absent following bone marrow IUT; • Donor-derived hematopoietic cells included osteoclasts and osteal macropha...

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Pubblicato in:Stem Cell Reports
Autori principali: Millard, Susan M., Pettit, Allison R., Ellis, Rebecca, Chan, Jerry K.Y., Raggatt, Liza J., Khosrotehrani, Kiarash, Fisk, Nicholas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
Soggetti:
Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649292/
https://ncbi.nlm.nih.gov/pubmed/26527386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.09.017
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