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The synapse and cytolytic machinery of cytotoxic T cells
Cytotoxic T lymphocytes (CTLs) rapidly kill target cells via the release of lytic granules into the immunological synapse, a process directed by the docking of the centrosome at the plasma membrane. New evidence highlights how signal strength and avidity influence the recruitment of cytolytic machin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101800/ https://ncbi.nlm.nih.gov/pubmed/20226643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.02.008 |
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