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The synapse and cytolytic machinery of cytotoxic T cells

Cytotoxic T lymphocytes (CTLs) rapidly kill target cells via the release of lytic granules into the immunological synapse, a process directed by the docking of the centrosome at the plasma membrane. New evidence highlights how signal strength and avidity influence the recruitment of cytolytic machin...

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Detalles Bibliográficos
Main Authors: Jenkins, Misty R, Griffiths, Gillian M
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101800/
https://ncbi.nlm.nih.gov/pubmed/20226643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.02.008
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