β-Arrestin-1 mediates thyrotropin-enhanced osteoblast differentiation

Thyrotropin (TSH) activation of the TSH receptor (TSHR), a 7-transmembrane-spanning receptor (7TMR), may have osteoprotective properties by direct effects on bone. TSHR activation by TSH phosphorylates protein kinases AKT1, p38α, and ERK1/2 in some cells. We found TSH-induced phosphorylation of thes...

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Autors principals: Boutin, Alisa, Eliseeva, Elena, Gershengorn, Marvin C., Neumann, Susanne
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2014
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101659/
https://ncbi.nlm.nih.gov/pubmed/24723693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-251124
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