O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41

Dysfunctions in Wnt signaling increase β-catenin stability and are associated with cancers, including colorectal cancer. In addition, β-catenin degradation is decreased by nutrient-dependent O-GlcNAcylation. Human colon tumors and colons from mice fed high-carbohydrate diets exhibited higher amounts...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Olivier-Van Stichelen, Stéphanie, Dehennaut, Vanessa, Buzy, Armelle, Zachayus, Jean-Luc, Guinez, Céline, Mir, Anne-Marie, El Yazidi-Belkoura, Ikram, Copin, Marie-Christine, Boureme, Didier, Loyaux, Denis, Ferrara, Pascual, Lefebvre, Tony
التنسيق: Artigo
اللغة:Inglês
منشور في: Federation of American Societies for Experimental Biology 2014
الموضوعات:
Research Communications
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101651/
https://ncbi.nlm.nih.gov/pubmed/24744147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-243535
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة