Cyclin D1 Stability Is Partly Controlled by O-GlcNAcylation

Cyclin D1 is the regulatory partner of the cyclin-dependent kinases (CDKs) CDK4 or CDK6. Once associated and activated, the cyclin D1/CDK complexes drive the cell cycle entry and G1 phase progression in response to extracellular signals. To ensure their timely and accurate activation during cell cyc...

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Bibliographische Detailangaben
Veröffentlicht in:Front Endocrinol (Lausanne)
Hauptverfasser: Masclef, Louis, Dehennaut, Vanessa, Mortuaire, Marlène, Schulz, Céline, Leturcq, Maïté, Lefebvre, Tony, Vercoutter-Edouart, Anne-Sophie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6395391/
https://ncbi.nlm.nih.gov/pubmed/30853938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00106
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