Polymerase I and transcript release factor (PTRF) regulates adipocyte differentiation and determines adipose tissue expandability

Impaired adipogenesis renders an adipose tissue unable to expand, leading to lipotoxicity and conditions such as diabetes and cardiovascular disease. While factors important for adipogenesis have been studied extensively, those that set the limits of adipose tissue expansion remain undetermined. Fee...

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Autori principali: Perez-Diaz, Sergio, Johnson, Lance A., DeKroon, Robert M., Moreno-Navarrete, Jose M., Alzate, Oscar, Fernandez-Real, Jose M., Maeda, Nobuyo, Arbones-Mainar, Jose M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2014
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101648/
https://ncbi.nlm.nih.gov/pubmed/24812087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-251165
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