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Starvation and inhibition of lysosomal function increased tau secretion by primary cortical neurons
Recent studies have demonstrated that human tau can be secreted by neurons and non-neuronal cells, an event linked to the propagation of tau pathology in the brain. In the present study, we confirmed that under physiological conditions, one tau-positive band was detected in the culture medium with a...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101526/ https://ncbi.nlm.nih.gov/pubmed/25030297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05715 |
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