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Treatment of hepatitis C with an interferon-based lead-in phase: A perspective from mathematical modeling

BACKGROUND: The standard of care for hepatitis C virus (HCV) genotype 1 is a protease inhibitor (telaprevir or boceprevir) combined with pegylated interferon and ribavirin (P/R). A lead-in phase of P/R therapy before addition of the protease inhibitor has been used, with the aim of improving respons...

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Hlavní autoři: Rong, Libin, Guedj, Jeremie, Dahari, Harel, Perelson, Alan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101064/
https://ncbi.nlm.nih.gov/pubmed/24434478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2725
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