Early Remodelling of Perinuclear Ca(2+) Stores and Nucleoplasmic Ca(2+) Signalling During the Development of Hypertrophy and Heart Failure

BACKGROUND: A hallmark of heart failure is impaired cytoplasmic Ca(2+) handling of cardiomyocytes. It remains unknown whether specific alterations in nuclear Ca(2+) handling – via altered excitation-transcription coupling – contribute to the development and progression of heart failure. METHODS AND...

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Autors principals: Ljubojevic, Senka, Radulovic, Snjezana, Leitinger, Gerd, Sedej, Simon, Sacherer, Michael, Holzer, Michael, Winkler, Claudia, Pritz, Elisabeth, Mittler, Tobias, Schmidt, Albrecht, Sereinigg, Michael, Wakula, Paulina, Zissimopoulos, Spyros, Bisping, Egbert, Post, Heiner, Marsche, Gunther, Bossuyt, Julie, Bers, Donald M., Kockskämper, Jens, Pieske, Burkert
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101040/
https://ncbi.nlm.nih.gov/pubmed/24928680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.008927
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