Transmission from centenarians to their offspring of mtDNA heteroplasmy revealed by ultra-deep sequencing

The role that mtDNA heteroplasmy plays in healthy aging, familial longevity and the heritability patterns of low levels heteroplasmy in the elderly are largely unknown. We analyzed the low levels of mtDNA heteroplasmy in blood in a cohort of centenarians, their offspring and a group of offspring of...

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Hlavní autoři: Giuliani, Cristina, Barbieri, Chiara, Li, Mingkun, Bucci, Laura, Monti, Daniela, Passarino, Giuseppe, Luiselli, Donata, Franceschi, Claudio, Stoneking, Mark, Garagnani, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100808/
https://ncbi.nlm.nih.gov/pubmed/25013208
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