Haploinsufficiency of Interferon Regulatory Factor 6 Alters Brain Morphology in the Mouse

Orofacial clefts are among the commonest birth defects. Among many genetic contributors to orofacial clefting, Interferon Regulatory Factor 6 (IRF6) is unique since mutations in this gene cause Van der Woude (VWS), the most common clefting syndrome. Furthermore, variants in IRF6 contribute to increa...

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Hlavní autoři: Aerts, Andrea, DeVolder, Ian, Weinberg, Seth M., Thedens, Dan, Dunnwald, Martine, Schutte, Brian C., Nopoulos, Peg
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100789/
https://ncbi.nlm.nih.gov/pubmed/24357509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.36333
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