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Haploinsufficiency of Interferon Regulatory Factor 6 Alters Brain Morphology in the Mouse
Orofacial clefts are among the commonest birth defects. Among many genetic contributors to orofacial clefting, Interferon Regulatory Factor 6 (IRF6) is unique since mutations in this gene cause Van der Woude (VWS), the most common clefting syndrome. Furthermore, variants in IRF6 contribute to increa...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100789/ https://ncbi.nlm.nih.gov/pubmed/24357509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.36333 |
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