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Functional CYP2B6 variants and virologic response to an efavirenz-containing regimen in Port-au-Prince, Haiti
OBJECTIVES: Efavirenz is widely prescribed for HIV-1 infection. Three polymorphisms in CYP2B6 define plasma efavirenz trough concentration strata that vary across an ∼10-fold range. We characterized associations between human genetic polymorphisms and virologic response among participants who receiv...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100704/ https://ncbi.nlm.nih.gov/pubmed/24695352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku088 |
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