CYP2B6 Variants and Plasma Efavirenz Concentrations during Antiretroviral Therapy in Port-au-Prince, Haiti

BACKGROUND: Polymorphisms in CYP2B6 are known to predict increased steady-state plasma concentrations of efavirenz. We characterized relationships between genetic polymorphisms and plasma efavirenz concentrations among 45 Haitians who initiated antiretroviral therapy in Port-au-Prince. METHODS: An o...

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Huvudupphovsmän: Leger, Paul, Dillingham, Rebecca, Beauharnais, Carole Anne, Kashuba, Angela D. M., Rezk, Naser L., Fitzgerald, Daniel W., Pape, Jean William, Haas, David W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754599/
https://ncbi.nlm.nih.gov/pubmed/19659438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/605126
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