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Purification, Preparation, and Use of Chaperone–Peptide Complexes for Tumor Immunotherapy

The molecular chaperone heat-shock protein 70 (Hsp70) possesses immune stimulatory properties that have been employed in the preparation of anticancer vaccines. Hsp70 binds antigenic peptides in the cytoplasm of cancer cells. Hsp70 thus serves as a convenient, non-discriminating transporter of antig...

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Autors principals: Murshid, Ayesha, Gong, Jianlin, Calderwood, Stuart K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100612/
https://ncbi.nlm.nih.gov/pubmed/23329490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-218-6_17
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