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Purification, Preparation, and Use of Chaperone–Peptide Complexes for Tumor Immunotherapy
The molecular chaperone heat-shock protein 70 (Hsp70) possesses immune stimulatory properties that have been employed in the preparation of anticancer vaccines. Hsp70 binds antigenic peptides in the cytoplasm of cancer cells. Hsp70 thus serves as a convenient, non-discriminating transporter of antig...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100612/ https://ncbi.nlm.nih.gov/pubmed/23329490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-218-6_17 |
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