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Acquired Dependence Of Acute Myeloid Leukemia On The DEAD-BOX RNA Helicase DDX5
Acute myeloid leukemia (AML) therapy involves compounds that are cytotoxic to both normal and cancer cells and relapsed AML is resistant to subsequent chemotherapy. Thus agents are needed that selectively kill AML cells with minimal toxicity. Here we report that AML is dependent on DDX5 and that inh...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100070/ https://ncbi.nlm.nih.gov/pubmed/24910429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.05.019 |
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