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Conserved Single Residue in the BK Potassium Channel Required for Activation by Alcohol and Intoxication in C. elegans

Alcohol directly modulates the BK potassium channel to alter behaviors in species ranging from invertebrates to humans. In the nematode Caenorhabditis elegans, mutations that eliminate the BK channel, SLO-1, convey dramatic resistance to intoxication by ethanol. We hypothesized that certain conserve...

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Detalhes bibliográficos
Main Authors: Davis, Scott J., Scott, Luisa L., Hu, Kevin, Pierce-Shimomura, Jonathan T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099540/
https://ncbi.nlm.nih.gov/pubmed/25031399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0838-14.2014
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