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Putative calcium-binding domains of the Caenorhabditis elegans BK channel are dispensable for intoxication and ethanol activation

Alcohol modulates the highly conserved, voltage- and calcium-activated potassium (BK) channel, which contributes to alcohol-mediated behaviors in species from worms to humans. Previous studies have shown that the calcium-sensitive domains, RCK1 and the Ca(2+) bowl, are required for ethanol activatio...

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Detalhes bibliográficos
Publicado no:Genes Brain Behav
Main Authors: Davis, S. J., Scott, L. L., Ordemann, G., Philpo, A., Cohn, J., Pierce-Shimomura, J. T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885643/
https://ncbi.nlm.nih.gov/pubmed/26113050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12229
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