11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice()

11β-Hydroxysteroid dehydrogenase-1 (11β-HSD1) plays a key role in glucocorticoid receptor (GR) activation. Besides, it metabolizes some oxysterols and bile acids (BAs). The GR regulates BA homeostasis; however, the impact of impaired 11β-HSD1 activity remained unknown. We profiled plasma and liver B...

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Detalhes bibliográficos
Main Authors: Penno, Carlos A., Morgan, Stuart A., Rose, Adam J., Herzig, Stephan, Lavery, Gareth G., Odermatt, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099504/
https://ncbi.nlm.nih.gov/pubmed/25061560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.04.008
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