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Presenilin Conditional Double Knockout Mice Exhibit Decreases in Drebrin A at Hippocampal CA1 Synapses

Presenilin conditional double knockout (PScDKO) mice have been used as animal models to study the development of Alzheimer’s disease (AD) phenotypes. Studies to date indicate that these animals exhibit memory dysfunction and decreased synaptic plasticity before the onset of neurodegeneration. Theref...

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Detalles Bibliográficos
Main Authors: LEE, DAVID, AOKI, CHIYE
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099411/
https://ncbi.nlm.nih.gov/pubmed/22715045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21578
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