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Increased Levels of NMDA Receptor NR2A Subunits at Pre- and Postsynaptic Sites of the Hippocampal CA1: An Early Response to Conditional Double Knockout of Presenilin 1 and 2

Greater than 90% of familial Alzheimer’s disease (AD) is linked to mutations of presenilin (PS), and the loss of PS function altogether within mouse brains by conditional double knockout of the PS 1 and 2 genes (PS-cDKO) leads to age-dependent emergence of AD phenotypes, including neurodegeneration...

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Detaylı Bibliyografya
Asıl Yazarlar: Aoki, Chiye, Lee, Joyce, Nedelescu, Hermina, Ahmed, Tunazzina, Ho, Angela, Shen, Jie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796344/
https://ncbi.nlm.nih.gov/pubmed/19795494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.22151
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