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Presenilin Conditional Double Knockout Mice Exhibit Decreases in Drebrin A at Hippocampal CA1 Synapses
Presenilin conditional double knockout (PScDKO) mice have been used as animal models to study the development of Alzheimer’s disease (AD) phenotypes. Studies to date indicate that these animals exhibit memory dysfunction and decreased synaptic plasticity before the onset of neurodegeneration. Theref...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4099411/ https://ncbi.nlm.nih.gov/pubmed/22715045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21578 |
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