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Detecting Novel Genetic Variants Associated with Isoniazid-Resistant Mycobacterium tuberculosis
BACKGROUND: Isoniazid (INH) is a highly effective antibiotic central for the treatment of Mycobacterium tuberculosis (MTB). INH-resistant MTB clinical isolates are frequently mutated in the katG gene and the inhA promoter region, but 10 to 37% of INH-resistant clinical isolates have no detectable al...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4099304/ https://ncbi.nlm.nih.gov/pubmed/25025225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102383 |
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