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Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure

A dynamic programming algorithm for prediction of RNA secondary structure has been revised to accommodate folding constraints determined by chemical modification and to include free energy increments for coaxial stacking of helices when they are either adjacent or separated by a single mismatch. Fur...

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Détails bibliographiques
Auteurs principaux: Mathews, David H., Disney, Matthew D., Childs, Jessica L., Schroeder, Susan J., Zuker, Michael, Turner, Douglas H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC409911/
https://ncbi.nlm.nih.gov/pubmed/15123812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401799101
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