Acute Myeloid Leukemia Following Myelodysplastic Syndrome and Failure of Therapy with Hypomethylating Agents: An Emerging Entity With a Poor Prognosis

We assessed outcome of 63 patients with acute myeloid leukemia (AML) arising from myelodysplastic syndrome (MDS) failing hypomethylating agents (HMA). Median age was 63 years. All 63 patients received at least 1 salvage regimen for AML and 35 patients (55%) received 2 or more. Of the 31 patients (49...

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Detalhes bibliográficos
Main Authors: Jabbour, Elias, Ghanem, Hady, Huang, Xuelin, Ravandi, Farhad, Garcia-Manero, Guillermo, O’Brien, Susan, Faderl, Stephan, Pierce, Sherry, Choi, Sangbum, Verstovsek, Srdan, Brandt, Mark, Cortes, Jorge, Kantarjian, Hagop
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098769/
https://ncbi.nlm.nih.gov/pubmed/24447728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2013.10.013
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