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Results of Phase II Randomized Study of Low-Dose Decitabine with or without Valproic Acid in Patients with Myelodysplastic Syndrome and Acute Myelogenous Leukemia
BACKGROUND: Hypomethylating agents have shown activity in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Pre-clinical and single-arm trials have suggested that adding histone deacetylase (HDAC) inhibitors may synergize the epigenetic modulation of hypomethylating agents and improve...
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| Publicado no: | Cancer |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320000/ https://ncbi.nlm.nih.gov/pubmed/25336333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29085 |
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