Results of Phase II Randomized Study of Low-Dose Decitabine with or without Valproic Acid in Patients with Myelodysplastic Syndrome and Acute Myelogenous Leukemia

BACKGROUND: Hypomethylating agents have shown activity in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Pre-clinical and single-arm trials have suggested that adding histone deacetylase (HDAC) inhibitors may synergize the epigenetic modulation of hypomethylating agents and improve...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer
Autors principals: Issa, Jean Pierre, Garcia-Manero, Guillermo, Huang, Xuelin, Cortes, Jorge, Ravandi, Farhad, Jabbour, Elias, Borthakur, Gautam, Brandt, Mark, Pierce, Sherry, Kantarjian, Hagop
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320000/
https://ncbi.nlm.nih.gov/pubmed/25336333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29085
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars