Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities

BACKGROUND: Outcome of patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) with chromosome 5 and 7 abnormalities [excluding del 5(q)] has been poor with fewer than 10% of patients alive at 2 years. METHODS: We investigated whether treatment with hypomethylating ag...

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Main Authors: Ravandi, Farhad, Issa, Jean-Pierre, Garcia-Manero, Guillermo, O’Brien, Susan, Pierce, Sherry, Shan, Jianqin, Borthakur, Gautam, Verstovsek, Srdan, Faderl, Stefan, Cortes, Jorge, Kantarjian, Hagop
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794953/
https://ncbi.nlm.nih.gov/pubmed/19795507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24661
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