Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury

We examined the effects of upregulation of heme oxygenase-1 (HO-1) in steatotic rat liver models of ex vivo cold ischemia/reperfusion (I/R) injury. In the model of ischemia/isolated perfusion, treatment of genetically obese Zucker rats with the HO-1 inducer cobalt protoporphyrin (CoPP) or with adeno...

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Main Authors: Amersi, Farin, Buelow, Roland, Kato, Hirohisa, Ke, Bibo, Coito, Ana J., Shen, Xiu-Da, Zhao, Delai, Zaky, Joseph, Melinek, Judy, Lassman, Charles R., Kolls, Jay K., Alam, J., Ritter, Thomas, Volk, Hans-Dieter, Farmer, Douglas G., Ghobrial, Rafik M., Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1999
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC409865/
https://ncbi.nlm.nih.gov/pubmed/10587527
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