Heme Oxygenase-1 Regulates Sirtuin-1 – Autophagy Pathway in Liver Transplantation: From Mouse-to-Human

Liver ischemia-reperfusion injury (IRI) represents a major risk factor of early graft dysfunction and a key obstacle to expanding the donor pool in orthotopic liver transplantation (OLT). Although graft autophagy is essential for resistance against hepatic IRI, its significance in clinical OLT remai...

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Veröffentlicht in:Am J Transplant
Hauptverfasser: Nakamura, Kojiro, Kageyama, Shoichi, Yue, Shi, Huang, Jing, Fujii, Takehiro, Ke, Bibo, Sosa, Rebecca A., Reed, Elaine F., Datta, Nakul, Zarrinpar, Ali, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910267/
https://ncbi.nlm.nih.gov/pubmed/29136322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14586
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