Sirtuin 1 Attenuates Inflammation and Hepatocellular Damage in Liver Transplant Ischemia/Reperfusion: From Mouse to Human

Hepatic ischemia/reperfusion injury (IRI), an inevitable antigen-independent inflammation response in cadaveric liver transplantation, correlates with poor early graft function, rejection episodes, and contributes to donor organ shortage. Sirtuin 1 (SIRT1) is a histone deacetylase that may regulate...

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Publicat a:Liver Transpl
Autors principals: Nakamura, Kojiro, Kageyama, Shoichi, Ke, Bibo, Fujii, Takehiro, Sosa, Rebecca A., Reed, Elaine F., Datta, Nakul, Zarrinpar, Ali, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705033/
https://ncbi.nlm.nih.gov/pubmed/28719070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.24821
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