Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice

To elucidate the role of cardiac myosin-binding protein-C (MyBP-C) in myocardial structure and function, we have produced mice expressing altered forms of this sarcomere protein. The engineered mutations encode truncated forms of MyBP-C in which the cardiac myosin heavy chain-binding and titin-bindi...

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Gepubliceerd in:J Clin Invest
Hoofdauteurs: McConnell, Bradley K., Jones, Karen A., Fatkin, Diane, Arroyo, Luis H., Lee, Richard T., Aristizabal, Orlando, Turnbull, Daniel H., Georgakopoulos, Dimitrios, Kass, David, Bond, Meredith, Niimura, Hideshi, Schoen, Frederick J., Conner, David, Fischman, Donald H., Seidman, Christine E., Seidman, J.G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1999
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10545522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7377
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