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Gene Expression Profiling of Extracellular Matrix as an Effector of Human Hepatocyte Phenotype in Primary Cell Culture

Previously, we demonstrated that primary cultures of rat hepatocytes evidence higher levels of differentiated function when cultured in the presence of a dilute overlay of extracellular matrix (Matrigel). In this investigation, we used DNA microarrays, quantitative RT-PCR, immunoblotting, and cell m...

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Main Authors: Page, Jeanine L., Johnson, Mary C., Olsavsky, Katy M., Strom, Steven C., Zarbl, Helmut, Omiecinski, Curtis J.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098128/
https://ncbi.nlm.nih.gov/pubmed/17329237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfm034
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