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Gene Expression Profiling of Extracellular Matrix as an Effector of Human Hepatocyte Phenotype in Primary Cell Culture

Previously, we demonstrated that primary cultures of rat hepatocytes evidence higher levels of differentiated function when cultured in the presence of a dilute overlay of extracellular matrix (Matrigel). In this investigation, we used DNA microarrays, quantitative RT-PCR, immunoblotting, and cell m...

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Autors principals: Page, Jeanine L., Johnson, Mary C., Olsavsky, Katy M., Strom, Steven C., Zarbl, Helmut, Omiecinski, Curtis J.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098128/
https://ncbi.nlm.nih.gov/pubmed/17329237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfm034
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