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EXPRESSION PROFILING OF INTERINDIVIDUAL VARIABILITY FOLLOWING XENOBIOTIC EXPOSURES IN PRIMARY HUMAN HEPATOCYTE CULTURES

In this investigation, we profiled interindividual variability of gene expression responses to three different prototypic chemical inducers in primary human hepatocyte cultures from ten independent donors. Correlation between basal expression in any two hepatocyte donors ranged from r(2) values of 0...

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Detalhes bibliográficos
Main Authors: Goyak, Katy M. O., Johnson, Mary C., Strom, Stephen C., Omiecinski, Curtis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610447/
https://ncbi.nlm.nih.gov/pubmed/18559280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.04.024
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