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In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor

[Image: see text] Cellular up-regulation of multidrug resistance protein 1 (MDR1) is a common cause for resistance to chemotherapy; development of third generation MDR1 inhibitors—several of which contain a common 6,7-dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline substructure—is underway. Eff...

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Bibliografske podrobnosti
Main Authors: Sprachman, Melissa M., Laughney, Ashley M., Kohler, Rainer H., Weissleder, Ralph
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098115/
https://ncbi.nlm.nih.gov/pubmed/24806886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500154c
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