Proteolytic Activation of the Porcine Epidemic Diarrhea Coronavirus Spike Fusion Protein by Trypsin in Cell Culture

Isolation of porcine epidemic diarrhea coronavirus (PEDV) from clinical material in cell culture requires supplementation of trypsin. This may relate to the confinement of PEDV natural infection to the protease-rich small intestine of pigs. Our study focused on the role of protease activity on infec...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wicht, Oliver, Li, Wentao, Willems, Lione, Meuleman, Tom J., Wubbolts, Richard W., van Kuppeveld, Frank J. M., Rottier, Peter J. M., Bosch, Berend Jan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Virus-Cell Interactions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097775/
https://ncbi.nlm.nih.gov/pubmed/24807723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00297-14
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