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Importin-α7 Is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice

Influenza A viruses recruit components of the nuclear import pathway to enter the host cell nucleus and promote viral replication. Here, we analyzed the role of the nuclear import factor importin-α7 in H1N1 influenza virus pulmonary tropism by using various ex vivo imaging techniques (magnetic reson...

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Autori principali: Resa-Infante, Patricia, Thieme, René, Ernst, Thomas, Arck, Petra C., Ittrich, Harald, Reimer, Rudolph, Gabriel, Gülsah
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097772/
https://ncbi.nlm.nih.gov/pubmed/24829333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00270-14
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