Protective Properties of Vaccinia Virus-Based Vaccines: Skin Scarification Promotes a Nonspecific Immune Response That Protects against Orthopoxvirus Disease

The process of vaccination introduced by Jenner generated immunity against smallpox and ultimately led to the eradication of the disease. Procedurally, in modern times, the virus is introduced into patients via a process called scarification, performed with a bifurcated needle containing a small amo...

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Detalhes bibliográficos
Main Authors: Rice, Amanda D., Adams, Mathew M., Lindsey, Scott F., Swetnam, Daniele M., Manning, Brandi R., Smith, Andrew J., Burrage, Andrew M., Wallace, Greg, MacNeill, Amy L., Moyer, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097768/
https://ncbi.nlm.nih.gov/pubmed/24760885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00185-14
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