Protective Properties of Vaccinia Virus-Based Vaccines: Skin Scarification Promotes a Nonspecific Immune Response That Protects against Orthopoxvirus Disease

The process of vaccination introduced by Jenner generated immunity against smallpox and ultimately led to the eradication of the disease. Procedurally, in modern times, the virus is introduced into patients via a process called scarification, performed with a bifurcated needle containing a small amo...

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Main Authors: Rice, Amanda D., Adams, Mathew M., Lindsey, Scott F., Swetnam, Daniele M., Manning, Brandi R., Smith, Andrew J., Burrage, Andrew M., Wallace, Greg, MacNeill, Amy L., Moyer, Richard W.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2014
נושאים:
Pathogenesis and Immunity
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097768/
https://ncbi.nlm.nih.gov/pubmed/24760885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00185-14
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